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Evolutionarily, the origin of RCD, in particular, apoptosis has been postulated to be associated with endosymbiosis, i.e., domestication of mitochondria [137,138,139]

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Plasma TMAO, and total carnitine (TC) levels were measured by the liquid chromatography-mass spectrometry system at the Mass Spectrometry Laboratory, Institute of Biochemistry and Biophysics, Polish Academy of Sciences (Warsaw, Poland) as described previously [18, 19]

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